灌注系統概述
HSE—HA生理學系統是一系列應用廣泛的完備產品,可用于整體動物生理學、立體或在體器官和組織灌注及組織浴槽研究。這些系統具有廣泛的應用,包括傳統的**藥理學、DMPK、毒理學、呼吸系統、心臟病學、分子生物學和生理學。每個系統都設計了標準的組件,再加一些其他配置以適合特殊研究的需要。。標注組件也意味著如果你是需要將現有設備配齊,或者進行系統升級,或者是完整的配套產品,你都只需要購買需要的構件。HSE-HA生理學系統為你提供各種工具,使你的研究走向多產和成功。
我們提供大多數生理學檢測設備,包括放大器、電極、傳感器和電化學檢測器。參數包括力、位移、壓力、液體和氣體流、心電圖(單導聯—12導聯系統)、MAP(單個或多個部位)、腦電圖、肌電圖、連續支流灌注傳統的血氣參數和電解質的分析,可以選擇程序化軟件和傳統的刺激器作為放大器、電極和傳感器等產品的補充。
HSE-DAQ系統產品家族(BDAS、ACAD、HAEMODYN、ISOHEART、PULMODYN、PENNOCK)可以記錄你的初始信號,計算到處的參數,注釋數據,快速簡易的輸入確定的數據用于分析。同時還可以選擇用于進一步分析的軟件模塊,帶狀記錄紙打印,自動和控制模塊等。產品經過預先設置,打開包裝即可使用,并專門設計符合你的系統配置和數據分析要求。
The Isolated Heart Size 5, IH-5, apparatus permits the use of hearts of small animals (rodents) as well as larger animals like rabbits. The flow limitation is about 500 ml/min. The perfusate is oxygenated in a 6 liter water jacketed reservoir with multiple ports for recirculation of the perfusate.
The system can be used for work in any one of three methods. The basic system is the retrograde perfusion mode (Langendorff). By setting a defined threshold pressure at the flow resistance, the system works under constant pressure; by increasing the threshold pressure to a supermaximal pressure (300 mmHg) the system works under constant flow. A working heart system can be arranged by using the Left Atrium Cannulating Option. The complete system is mounted on a compact acrylic stand.
The system can also be used to simultaneously record all hemodynamic parameters as well as 8 AP-potentials and a 12-lead ECG. For this purpose, the IH-5 unit is additionally equipped with a circular holder for 8 MAP-electrodes and with an ECG multi-electrode insert in the heart chamber.
• High perfusion pressure (up to 300 mmHg); easy and fast changes of the perfusion pressure (within seconds)
• Continuous measurement of heart mechanics (contractility, segment lengths), bioelectrical signals (ECG, MAP) and perfusate characteristics (pCO2, pO2, pH)
• The system can easily be modified to a working heart system, the special flow resistance and compliance chamber mimics closely the in-vivo afterload
• Multiple monophasic action potentials (MAP) and simultaneous multilead ECG recording from Isolated Perfused Rabbit heart
• Extended system for hemodynamic and electrophysiology studies
• Applications:– Dispersion of ventricular repolarization