灌注系統概述
HSE—HA生理學系統是一系列應用廣泛的完備產品，可用于整體動物生理學、立體或在體器官和組織灌注及組織浴槽研究。這些系統具有廣泛的應用，包括傳統的**藥理學、DMPK、毒理學、呼吸系統、心臟病學、分子生物學和生理學。每個系統都設計了標準的組件，再加一些其他配置以適合特殊研究的需要。。標注組件也意味著如果你是需要將現有設備配齊，或者進行系統升級，或者是完整的配套產品，你都只需要購買需要的構件。HSE-HA生理學系統為你提供各種工具，使你的研究走向多產和成功。
我們提供大多數生理學檢測設備，包括放大器、電極、傳感器和電化學檢測器。參數包括力、位移、壓力、液體和氣體流、心電圖（單導聯—12導聯系統）、MAP（單個或多個部位）、腦電圖、肌電圖、連續支流灌注傳統的血氣參數和電解質的分析，可以選擇程序化軟件和傳統的刺激器作為放大器、電極和傳感器等產品的補充。
HSE-DAQ系統產品家族（BDAS、ACAD、HAEMODYN、ISOHEART、PULMODYN、PENNOCK）可以記錄你的初始信號，計算到處的參數，注釋數據，快速簡易的輸入確定的數據用于分析。同時還可以選擇用于進一步分析的軟件模塊，帶狀記錄紙打印，自動和控制模塊等。產品經過預先設置，打開包裝即可使用，并專門設計符合你的系統配置和數據分析要求。
• Constant pressure or constant flow perfusion of isolated rodent hearts with the same apparatus
• Compact unit improved for low volume and high temperature stability
• High perfusion pressure possible (up to 300 mmHg)
• Continuous measurement of heart mechanics and bioelectrical signals
• Langendorff or Working Heart Configurations – Easy to Upgrade
• The special flow resistance and compliance chamber closely mimics the in-vivo afterload
• Applications:
– Testing inotropic and vasoactive substances
– Testing cardiac rhythm (chronotropic and arrythmogenic effects)
– Assessment of the refractory period
– Cardiovascular screening of transgenic mice
The IH-SR apparatus has been designed for experiments on the isolated heart of small rodents like rats or guinea pigs, and especially mice. Available in two versions: LH = Langendorff Heart and WH = Working Heart. Both versions allow easy conversion between constant pressure and constant flow conditions. The WH version of the apparatus allows isolated heart experiments in both LH or WH mode. Mode changeover is performed through a few simple manipulations; no additional conversion of the apparatus required. The precision design simplifies system use and minimizes user error.
In LH mode, the coronary vessels are perfused by retrograde flow through the aorta. Under constant pressure conditions, coronary flow can be measured with a flow probe while in constant flow experiments, the perfusion pressure can be measured with a pressure transducer. Measurement of isovolumetirc left ventricular pressure (LVP) (balloon method) is facilitated by custom LVP balloon catheters.
In WH mode the left atrium is cannulated and the heart performs pressure-volume work. Atrial preload is set by a simple fluid column height adjustment. Measurable parameters in WH mode include perfusion pressure, aortic flow, total cardiac output from left atrial flow, atrial preload pressure, LVP pressure via aortic cannulation or ventricular cannulation.
Parameters that can be monitored in either LH or WH modes include ECG, and Monophasic Action Potential. Traditional blood gas measurements (pO2, pCO2 and pH) as well as ion concentrations can also be monitored by pulmonary artery cannulation in rats and guinea pigs but is not available for mice.
• Constant pressure or constant flow perfusion of isolated rodent hearts with the same apparatus
• Compact unit improved for low volume and high temperature stability
• High perfusion pressure possible (up to 300 mmHg)
• Continuous measurement of heart mechanics and bioelectrical signals
• Langendorff or Working Heart Configurations – Easy to Upgrade
• The special flow resistance and compliance chamber closely mimics the in-vivo afterload
• Applications:
– Testing inotropic and vasoactive substances
– Testing cardiac rhythm (chronotropic and arrythmogenic effects)
– Assessment of the refractory period
– Cardiovascular screening of transgenic mice